Fluoxetine leads to better response in major depressive disorder among Han-Chinese patients with the 5-HTTLPR l/l genotype compared with s allele carriers, as evaluated on the basis of total (P = 0.013), core (P = 0.011), and psychic-anxiety (P = 0.005) and somatic-anxiety (P = 0.002) Hamilton Depression Rating Scale-score percentage change.
(N= 121 patients with major depressive disorder; Han-Chinese sample population of Taiwan).
(Yu et al., 2002)