Han-Chinese patients with major depressive disorder and the 5-HTTLPR l/l genotype had a significantly better response to fluoxetine when compared with s allele carriers, as evaluated on the basis of total (P = 0.013), core (P = 0.011), and psychic-anxiety (P = 0.005) and somatic-anxiety (P = 0.002) Hamilton Depression Rating Scale-score percentage change, confirming previous western reports.

(N= 121 patients with major depressive disorder; Han-Chinese sample population of Taiwan)ring the 5-HTTLPR l/l
(Yu et al., 2002)