Female hispanic patients with major depressive disorder reported fewer side effects when treated with paroxetine (or fluoxetine) compared to non-Hispanic female patients.
Hispanic patients had 2.2 +/- 2.0 side effect complaints versus 5.1 +/- 2.5 for non-Hispanic patients (p<0.005). No differences were reported in response (HAM-D scores), side effects, or attrition rates between fluoxetine- and paroxetine-treated subjects.
N = 26: 13 Hispanic and 13 non-Hispanic patients in San Diego, Cal., prospective open-label study of paroxetine (N=18) and fluoxetine (N=8); Alonso et al., 1997.