Drug-naive Chinese first-episode patients improve on low risperidone dose.
In this naturalistic study a mean (SD) daily dose of RSP prescribed was 1.47 (0.56) mg. resulted in a mean (SD) reduction in PANSS score from 64.58 (3.33) at baseline to 41.32 (2.20) at week 12. There was a significant correlation between weight-normalized dose of ripseridone and 9-OH-risperidone plasma levels, but not risperidone plasma levels.
Nineteen Chinese consecutive referrals to the inpatient and outpatient services of the Early Psychosis Intervention Programme, Singapore (10 men and 9 women with a mean (SD) age of 28.74 (6.7) years).
(Verma et al., 2005)